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Use caution Drug recall · FDA · Published April 6, 2020

The Medicine Shoppe Recalls Bi-Est Hormone Compound Due to Processing Errors

The Medicine Shoppe Pharmacy recalls one bottle of Bi-Est (1:1)/Progesterone/Testosterone due to lack of processing control. Check your lot number.

Plain-English summary generated from official FDA data by GovInfoNow · Published by Carlos Caban · How we make summaries

🇺🇸 FDA recall #D-1217-2020DrugThe Medicine Shoppe Pharmacy ›
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Contact the company

Recalling firmThe Medicine Shoppe Pharmacy3524b Tamiami Trl · Port Charlotte, FL 33952-8100
✎ GovInfoNow plain-language explainer

What happened, in plain English

The Medicine Shoppe Pharmacy is recalling a specific 90 mL bottle of their compounded hormone medication, Bi-Est (1:1)/Progesterone/Testosterone. The recall was initiated because the product suffered from a lack of processing control during manufacturing. This issue affects only one bottle distributed in Florida. Read more at govinfonow.com/recall/37148-the-medicine-shoppe-recalls-bi-est-hormone-compound-due-to.

Source Summary by GovInfoNow · govinfonow.com/recall/37148-the-medicine-shoppe-recalls-bi-est-hormone-compound-due-to · Updated October 11, 2026 · FDA enforcement record: FDA #D-1217-2020

Cite this page

“The Medicine Shoppe Recalls Bi-Est Hormone Compound Due to Processing Errors.” GovInfoNow, updated October 11, 2026. https://govinfonow.com/recall/37148-the-medicine-shoppe-recalls-bi-est-hormone-compound-due-to. Based on FDA recall #D-1217-2020 (https://api.fda.gov/drug/enforcement.json?search=recall_number:%22D-1217-2020%22&limit=1).

Why it’s dangerous

The hazard is defined as a lack of processing control, which means the manufacturing process may have been inconsistent or incorrect. This could potentially affect the potency, purity, or safety of the hormone medication, though specific injury details are not provided in the record.

Who’s affected

Patients in Florida who purchased this specific compounded hormone prescription from The Medicine Shoppe Pharmacy are affected. Individuals holding lot number 45280 are at risk of receiving a product that did not meet processing standards.

How to tell if you have this one

Check if you have a 90 mL bottle of Bi-Est (1:1)/Progesterone/Testosterone 2.5/150/1.5 mg/mL Versabase CR from The Medicine Shoppe Pharmacy. Look for lot number 45280 on the label. The product was distributed in Florida.

  • Brand
    The Medicine Shoppe Pharmacy
  • Category
    Drug
FDA recall event · 54 products

All 54 products in this recall

FDA lists each product line separately under one recall event. Check your product description, lot or code numbers against each row. Every row shares the hazard and remedy on this page.

  • Classification
    Class II
  • Status
    Terminated
  • Distribution
    Florida
Recall numberProduct, codes & lotsQuantity
D-1175-2020Estriol Vaginal Cream (0.1%) 1 mg Cream 30 GM tubes, Rx, The Medicine Shoppe Pharmacy, Port Charlotte, FL; Lot: 45036 Discard by: 7/31/2020; 45075 Discard by:8/7/20208 tubes
D-1176-2020Testosterone W/Cosmetic HRT Base 100 MG (10%) Cream 30 GM, tubes Rx, The Medicine Shoppe Pharmacy, Port Charlotte, FL; Lot: 45027 Discard by: 07/27/20204 tubes
D-1177-2020Fluorouracil (5-FU) 4.5% Cream 100 GM, tube Rx, The Medicine Shoppe Pharmacy, Port Charlotte, FL; Lot: 45044 Discard by: 8/2/20201 tube
D-1178-2020Bi-Est8:2/Progesterone/Testosterone 1.0/50 MG/.5MG/ML Cream 30 GM tube, Rx, The Medicine Shoppe Pharmacy, Port Charlotte, FL; Lot: 44767 Discard by: 5/17/20202 tubes
D-1179-2020Bi-Est8:2/Progesterone/Testosterone 1.0/50 MG/.5MG/ML Cream 30 GM, tube Rx, The Medicine Shoppe Pharmacy, Port Charlotte, FL; Lot: 44639 Discard by: 11/28/20201 tube
D-1180-2020Naltrexone (Loxoral) 4.5 mg Capsules, 60 count bottle, Rx, The Medicine Shoppe Pharmacy, Port Charlotte, FL; Lot: 44898 Discard by: 3/23/20201 bottle
D-1181-2020Estradiol/Progesterone/Testosterone 1.5/100/1.25 mg/mL Cream 30 gm tube, Rx, The Medicine Shoppe Pharmacy, Port Charlotte, FL; Lot: 44560 Discard by: 03/24/20201 tube
D-1182-2020Estradiol Vag Cream 0.01% Cream 30 gm tube, Rx, The Medicine Shoppe Pharmacy, Port Charlotte, FL; Lot: 44967 Discard by: 7/10/2020; 45171 Discard by: 9/2/20207 tubes
D-1183-2020Testosterone w/ Atrevis 20 mg (2%) Cream 30 gm tube, Rx, The Medicine Shoppe Pharmacy, Port Charlotte, FL; Lot: 44965 Discard by: 7/10/20201 tube
D-1184-2020Testosterone w/ Atrevis 100 mg/mL GEL, 90 gm pump, Rx, The Medicine Shoppe Pharmacy, Port Charlotte, FL; Lot: 45114 Discard by: 08/20/2020; 45139 Discard by: 8/27/20203 bottles
D-1185-2020Estradiol 1.8 mg capsule 30 cap bottle, Rx, The Medicine Shoppe Pharmacy, Port Charlotte, FL; Lot: 45073 Discard by: 8/7/20201 bottle
D-1186-2020Bi-Est (1:1) Progest/Test 0.5 mg/40 mg/10.5 mg/mL Cream 30 gm tube, Rx, The Medicine Shoppe Pharmacy, Port Charlotte, FL; Lot: 44894 Discard by: 6/15/20201 tube
D-1187-2020Bi-Est (8:2) Progest/Test 2/80/3 mg/mL cream 30 gm tube, Rx, The Medicine Shoppe Pharmacy, Port Charlotte, FL; Lot: 45098 Discard by: 8/16/20201 tube
D-1188-2020Bi-Est (1:1) Progest/Test 0.5 mg/1.5 mg/mL cream 60 gm tube, Rx, The Medicine Shoppe Pharmacy, Port Charlotte, FL; Lot: 45100 Discard by: 8/16/20201 tube
D-1189-2020Bi-Est (1:1) Progesterone/Testost 1.0 mg/60 mg/0.5 mg/mL Cream 60 gm tube, Rx, The Medicine Shoppe Pharmacy, Port Charlotte, FL; Lot: 45116 Discard by: 8/22/20201 tube
D-1190-2020Progesterone/Versa Base 20 mg (2%) Cream 30 gm tube, Rx, The Medicine Shoppe Pharmacy, Port Charlotte, FL; Lot: 45104 Discard by: 8/18/20201 tube
D-1191-2020Progesterone 200 mg Capsules 90 capsules, Rx, The Medicine Shoppe Pharmacy, Port Charlotte, FL; Lot: 45106 Discard by: 8/16/2020; 45128 Discard by: 8/25/2020; 45227 Discard by: 9/14/20203 bottles
D-1192-2020Bi-Est 1:1/Progesterone/Testosterone 1mg/40 mg/0.5 mg/mL Cream 30 gm tube, Rx, The Medicine Shoppe Pharmacy, Port Charlotte, FL; Lot: 45108 Discard by: 8/18/20201 tube
D-1193-2020Bi-Est (8:2)/DHEA/Testosterone 0.8 mg/ 9/0.4 mg/0.2 mg/mL Cream 6 gm tube, Rx, The Medicine Shoppe Pharmacy, Port Charlotte, FL; Lot: 44798 Discard by: 5/22/20201 tube
D-1194-2020Hydroquinone/Fluocinolone/Tretonoin/Kojic Acid 4/0.01/0.05/2% Cream 30 gm tube, Rx, The Medicine Shoppe Pharmacy, Port Charlotte, FL; Lot: 45077 Discard by: 3/12/20201 tube
D-1195-2020Ergotamine Tartrate 1 mg/Caffeine 100 mg Base Suppository (Pink) 48 count box, Rx, The Medicine Shoppe Pharmacy, Port Charlotte, FL; Lot: 45247 Discard by: 9/19/20201 box
D-1196-2020Diethylstilbestrol 1 mg capsule 300 capsules bottle, Rx, The Medicine Shoppe Pharmacy, Port Charlotte, FL; Lot: 45102 Discard by: 8/17/20201 bottle
D-1197-2020Bi-Est 8:2/Progesterone 2.5 mg/150/mL Cream 30 gm tube, Rx, The Medicine Shoppe Pharmacy, Port Charlotte, FL; Lot: 44908 Discard by: 6/17/20201 tube
D-1198-2020Bi-Est 8:2/Progesterone/Testosterone DHEA 4.0/100/1/25.0 mg capsules 90 capsules bottle, Rx, The Medicine Shoppe Pharmacy, Port Charlotte, FL; Lot: 45130 Discard by: 8/25/20201 bottle
D-1199-2020Bi-Est 1:1/Progesterone/Testosterone 2.0/100/0.25 mg/mL Cream 30 gm tube, Rx, The Medicine Shoppe Pharmacy, Port Charlotte, FL; Lot: 45023 Discard by: 7/27/2020; 45268 Discard by: 9/27/20202 tubes
D-1200-2020Bi-Est 1:1/Progest/DHEA 1/40/5 mg/mL Cream 30 mL jar, Rx, The Medicine Shoppe Pharmacy, Port Charlotte, FL; Lot: 45146 Discard by: 8/30/20201 jar
D-1201-2020Bi-Est 1:1/Progest/DHEA 0.5 mg/180 mg/25 mg/mL Cream 30 mL jar, Rx, The Medicine Shoppe Pharmacy, Port Charlotte, FL; Lot: 44850 Discard by: 6/4/20201 tube
D-1202-2020Bi-Est (8:2)/Progest/Test/DHEA 6/50/0.5/10 mg/mL Cream 30 mL, Rx, The Medicine Shoppe Pharmacy, Port Charlotte, FL; Lot: 45148 Discard by: 8/30/20201 tube
D-1203-2020Bi-Est (50/50)/Progesterone 1.25 mg/80 mL Cream 30 gm tube, Rx, The Medicine Shoppe Pharmacy, Port Charlotte, FL; Lot: 45006 Discard by: 7/18/2020; 45251 Discard by: 9/22/20202 tubes
D-1204-2020Testosterone in Atrevis 50 mg/mL Gel 30 gm tube, Rx, The Medicine Shoppe Pharmacy, Port Charlotte, FL; Lot: 44488 Discard by: 8/22/20201 tube
D-1205-2020Paregoric Compound (contains Morphine) Solution 480 mL bottle, Rx, The Medicine Shoppe Pharmacy, Port Charlotte, FL; Lot: 45161 Discard by: 5/4/20201 bottle
D-1206-2020Hydromorphone Oral 1 mg/mL Solution 240 mL, bottle, Rx, The Medicine Shoppe Pharmacy, Port Charlotte, FL; Lot: 45163 Discard by: 9/1/20201 bottle
D-1207-2020Clobetasol Mouth Rinse 0.05% Solution 450 mL bottle, Rx, The Medicine Shoppe Pharmacy, Port Charlotte, FL; Lot: 45169 Discard by: 9/2/20201 bottle
D-1208-2020Naltrexone 4.5 mg/mL Suspension 30 mL bottle, Rx, The Medicine Shoppe Pharmacy, Port Charlotte, FL; Lot: 45177 Discard by: 9/4/20201 bottle
D-1209-2020Estriol 5 mg Suppository 36 each box, Rx, The Medicine Shoppe Pharmacy, Port Charlotte, FL; Lot: 45179 Discard by: 9/5/20201 box
D-1210-2020Hydrocortisone in Aquaphor/Therapeutic Moisturizing Cream 100 gm tube, Rx, The Medicine Shoppe Pharmacy, Port Charlotte, FL; Lot: 45211 Discard by: 9/9/20201 tube
D-1211-2020Hydrocortisone 2.5%/Econazole 1% 50/50 Using Powder 25%/1% Cream 60 gm tube, Rx, The Medicine Shoppe Pharmacy, Port Charlotte, FL; Lot: 45212 Discard by: 9/9/20201 tube
D-1212-2020Bi-Est (1:1)/Progesterone/Testosterone 2.0 mg/40 mg/1.0 mg/mL Cream 30 gm tube, Rx, The Medicine Shoppe Pharmacy, Port Charlotte, FL; Lot: 44892 Discard by: 4/15/20201 tube
D-1213-2020Bi-Est (50/50)/Progesterone/Testosterone 1.5 mg/40 mg/0.5 mg/mL Cream 30 gm tube, Rx, The Medicine Shoppe Pharmacy, Port Charlotte, FL; Lot: 44840 Discard by: 6/1/20201 tube
D-1214-2020Bi-Est (50/50)/Progesterone/Testost 1.5/100/0.5 mg Cream 30 gm tube, Rx, The Medicine Shoppe Pharmacy, Port Charlotte, FL; Lot: 45132 Discard by: 8/26/20201 jar
D-1215-2020Bi-Est (8:2)/Progesterone 2/100 mg/mL capsule 90 caps bottle, Rx, The Medicine Shoppe Pharmacy, Port Charlotte, FL; Lot: 45239 Discard by: 9/16/20201 bottle
D-1216-2020Bi-Est (50/50/Progesterone 0.2 mg/70 mg Cream 30 gm jar, Rx, The Medicine Shoppe Pharmacy, Port Charlotte, FL; Lot: 45110 Discard by: 8/20/20201 jar
D-1217-2020Bi-Est (1:1)/Progesterone/Testosterone 2.5/150/1.5 mg/mL Versabase CR 90 mL bottle, Rx, The Medicine Shoppe Pharmacy, Port Charlotte, FL; Lot: 45280 Discard by: 9/23/20201 bottle
D-1218-2020Bi-Est (8:2)/Progesterone/Testosterone 0.5/75 mg per 0.2 mL Cream 6 mL jar, Rx, The Medicine Shoppe Pharmacy, Port Charlotte, FL; Lot: 44518 Discard by: 3/15/20201 jar
D-1219-2020Estriol/Testosterone Vaginal 0.1/0.1% Cream 30 gm jar, Rx, The Medicine Shoppe Pharmacy, Port Charlotte, FL; Lot: 45221 Discard by: 9/12/20201 jar
D-1220-2020Paregoric Alternate Elixir 300 mL bottle, Rx, The Medicine Shoppe Pharmacy, Port Charlotte, FL; Lot: 45231 Discard by: 6/16/20201 bottle
D-1221-2020Progesterone/Natacream 20 mg/2% mL Cream 60 gm jar, Rx, The Medicine Shoppe Pharmacy, Port Charlotte, FL; Lot: 45233 Discard by: 9/15/20201 jar
D-1222-2020Testosterone in Atrevis 75 mg/mL Gel 90 GMS tube, Rx, The Medicine Shoppe Pharmacy, Port Charlotte, FL; Lot: 45235 Discard by: 9/15/20201 tube
D-1223-2020Ketoprofen/DMSO 20%/10% Lipoderm 50 gm jar, Rx, The Medicine Shoppe Pharmacy, Port Charlotte, FL; Lot: 44552 Discard by: 3/23/20201 jar
D-1224-2020Testosterone w/Cosmetic HRT Base 20 mg (2%) Cream 30 GM jar, Rx, The Medicine Shoppe Pharmacy, Port Charlotte, FL; Unknown1 jar
D-1225-2020Tretinoin 0.1% in Versabase Cream 0.1% Versabase CR 45 gm jar, Rx, The Medicine Shoppe Pharmacy, Port Charlotte, FL; Lot: 45240 Discard by: 6/18/20201 jar
D-1226-2020Ergotamine Tartrate 1 mg/Caffeine 100 mg base F Suppository (Pink) 48 suppositories, Rx, The Medicine Shoppe Pharmacy, Port Charlotte, FL; Lot: 45247 Discard by: 9/19/20202 boxes
D-1227-2020Betahistine 16 mg Capsule 180 capsules bottle, Rx, The Medicine Shoppe Pharmacy, Port Charlotte, FL; Lot: 45266 Discard by: 9/26/20202 bottles
D-1228-2020Levothyroxin (T4)/Liothyronine (T3) SR 130 mg/175 mg capsule 21 capsules bottle, Rx, The Medicine Shoppe Pharmacy, Port Charlotte, FL; Lot: 45274 Discard by: 9/27/20201 bottle
Based on the official FDA remedy

What to do — step by step

  1. Check Your Lot Number

    Verify if your bottle has lot number 45280 and a discard by date of 9/23/2020.

  2. Discard the Product

    The record states 'Discard by: 9/23/2020', indicating the product should not be used after this date or if identified as part of the recall.

    2020-09-23

Where it went and when

Where it was distributed

Distributed in Florida.

Alaska: not listedAKMaine: not listedMEVermont: not listedVTNew Hampshire: not listedNHWashington: not listedWAIdaho: not listedIDMontana: not listedMTNorth Dakota: not listedNDMinnesota: not listedMNIllinois: not listedILWisconsin: not listedWIMichigan: not listedMINew York: not listedNYRhode Island: not listedRIMassachusetts: not listedMAOregon: not listedORNevada: not listedNVWyoming: not listedWYSouth Dakota: not listedSDIowa: not listedIAIndiana: not listedINOhio: not listedOHPennsylvania: not listedPANew Jersey: not listedNJConnecticut: not listedCTCalifornia: not listedCAUtah: not listedUTColorado: not listedCONebraska: not listedNEMissouri: not listedMOKentucky: not listedKYWest Virginia: not listedWVVirginia: not listedVAMaryland: not listedMDDelaware: not listedDEArizona: not listedAZNew Mexico: not listedNMKansas: not listedKSArkansas: not listedARTennessee: not listedTNNorth Carolina: not listedNCSouth Carolina: not listedSCDistrict of Columbia: not listedDCOklahoma: not listedOKLouisiana: not listedLAMississippi: not listedMSAlabama: not listedALGeorgia: not listedGAHawaii: not listedHITexas: not listedTXFlorida: yesFL

FDA distribution: “Florida” States read from FDA’s own wording; “not listed” means the notice does not name it.

States: Florida.

Recall timeline

FDA terminated this recall 2.7 years after the firm started it.

1. Firm started the recall: Apr 6, 202012. FDA classified it Class II: Apr 10, 202023. Published in FDA’s Enforcement Report: Apr 22, 202034. FDA terminated the recall: Dec 13, 2022420202022
  1. Firm started the recall
  2. FDA classified it Class II
  3. Published in FDA’s Enforcement Report
  4. FDA terminated the recall

Dates from the agency record only; steps without a date are left out.

✎ GovInfoNow

Questions people ask

From the GovInfoNow team · based on the FDA notice · How we make summaries

Where was this product sold or distributed?

The distribution pattern for this recall is Florida.

How many bottles are affected by this recall?

The recall covers only one bottle (product quantity: 1 bottle).

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Keep exploring

Where this comes from

The facts (hazard, remedy, dates, manufacturer) are pulled from the official FDA recall record. The plain-language summary and step-by-step checklist are written by GovInfoNow to make the official notice easier to act on — they don’t replace it.

  • Official source: FDA Recall #D-1217-2020 (April 6, 2020) — FDA publishes no per-recall page; this is the official machine-readable enforcement record. Search FDA recalls for D-1217-2020 to see it in context.
  • Plain-language summary written by qwen3.6:35b-a3b on October 11, 2026, from the official record above. Not reviewed by a person — if it conflicts with the FDA notice, the notice is correct. Report an error on this page.
  • GovInfoNow is an independent service and is not a government agency. We republish official FDA recall data; we don’t issue, amend or administer recalls.
GovInfoNow is an independent guide. We are not FDA or any government agency. Always confirm details with the official recall.Data: CPSC · FDA · NHTSA · USDA