Is Lidocaine Hydrochloride Injection (Xylocaine) in shortage?
Yes. Lidocaine Hydrochloride Injection is on FDA’s drug shortage list (unavailable), last updated Oct 6, 2026.
Why it’s in shortage
- Demand increase for the drug
- Other
Every listed package
FDA tracks shortages per package. What each maker reports, most recently updated first:
- Lidocaine Hydrochloride In Plastic Container, Injection, 10 mg/1 mL (NDC 63323-201-02)
Check wholesalers for inventory
Maker contact: 888-386-1300
- Lidocaine Hydrochloride, Injection, 10 mg/1 mL (NDC 63323-201-10)
Next release October 2026. Check wholesalers for inventory.
Maker contact: 888-386-1300
- Lidocaine Hydrochloride, Injection, 20 mg/1 mL (NDC 63323-202-02)
Check wholesalers for inventory
Maker contact: 888-386-1300
- Xylocaine, Injection, 5 mg/1 mL (NDC 63323-484-57)
Estimated recovery: TBD
Maker contact: 888-386-1300
- Xylocaine, Injection, 10 mg/1 mL (NDC 63323-485-27)
Check wholesalers for inventory
Maker contact: 888-386-1300
- Xylocaine, Injection, 20 mg/1 mL (NDC 63323-486-17)
Check wholesalers for inventory
Maker contact: 888-386-1300
- Xylocaine, Injection, 20 mg/1 mL (NDC 63323-486-57)
Check wholesalers for inventory
Maker contact: 888-386-1300
- Xylocaine, Injection, 5 mg/1 mL (NDC 63323-491-57)
Check wholesalers for inventory
Maker contact: 888-386-1300
- Xylocaine, Injection, 10 mg/1 mL (NDC 63323-492-31)
Estimated recovery: TBD
Maker contact: 888-386-1300
- Xylocaine, Injection, 10 mg/1 mL (NDC 63323-492-37)
Check wholesalers for inventory
Maker contact: 888-386-1300
- Xylocaine, Injection, 10 mg/1 mL (NDC 63323-492-57)
Check wholesalers for inventory
Maker contact: 888-386-1300
- Xylocaine, Injection, 15 mg/1 mL (NDC 63323-493-91)
Estimated recovery: TBD
Maker contact: 888-386-1300
- Xylocaine, Injection, 15 mg/1 mL (NDC 63323-493-97)
Estimated recovery: TBD
Maker contact: 888-386-1300
- Xylocaine, Injection, 20 mg/1 mL (NDC 63323-495-27)
Check wholesalers for inventory
Maker contact: 888-386-1300
- Xylocaine, Injection, 20 mg/1 mL (NDC 63323-496-97)
Estimated recovery: TBD
Maker contact: 888-386-1300
- Lidocaine Hydrochloride, Injection, 100 mg/10 mL (NDC 83634-651-10)
Distributed by Avenacy, LLC
Maker contact: Avenacy, LLC: 877-283-6229
- Lidocaine Hydrochloride, Injection, 200 mg/20 mL (NDC 83634-651-20)
Distributed by Avenacy, LLC
Maker contact: Avenacy, LLC: 877-283-6229
- Lidocaine Hydrochloride, Injection, 500 mg/50 mL (NDC 83634-651-50)
Distributed by Avenacy, LLC
Maker contact: Avenacy, LLC: 877-283-6229
- Lidocaine Hydrochloride, Injection, 20 mg/2 mL (NDC 83634-653-02)
Distributed by Avenacy, LLC
Maker contact: Avenacy, LLC: 877-283-6229
- Lidocaine Hydochloride, Injection, 50 mg/5 mL (NDC 83634-653-05)
Distributed by Avenacy, LLC
Maker contact: Avenacy, LLC: 877-283-6229
- Lidocaine Hydrochloride, Injection, 300 mg/30 mL (NDC 83634-653-30)
Distributed by Avenacy, LLC
Maker contact: Avenacy, LLC: 877-283-6229
- Lidocaine Hydrochloride And Dextrose, Injection, 4 mg/1 mL (NDC 0338-0409-03)
Maker contact: 888-229-0001
- Lidocaine Hydrochloride And Dextrose, Injection, 8 mg/1 mL (NDC 0338-0411-02)
Maker contact: 888-229-0001
- Lidocaine Hydrochloride, Injection, 10 mg/1 mL (NDC 55150-159-74)
On backorder. Recovery: TBD. Check wholesalers for inventory
Maker contact: 888-238-7880
- Lidocaine Hydrochloride, Injection, 10 mg/1 mL (NDC 55150-161-02)
On backorder. Recovery: mid-October 2026. Check wholesalers for inventory
Maker contact: 888-238-7880
- Lidocaine Hydrochloride, Injection, 10 mg/1 mL (NDC 55150-162-05)
Check wholesalers for inventory
Maker contact: 888-238-7880
- Lidocaine Hydrochloride, Injection, 10 mg/1 mL (NDC 55150-163-30)
Check wholesalers for inventory
Maker contact: 888-238-7880
- Lidocaine Hydrochloride, Injection, 20 mg/mL (NDC 55150-164-02)
Check wholesalers for inventory
Maker contact: 888-238-7880
- Lidocaine Hydrochloride, Injection, 20 mg/1 mL (NDC 55150-165-05)
On backorder. Recovery: mid-October 2026. Check wholesalers for inventory
Maker contact: 888-238-7880
- Lidocaine Hydrochloride, Injection, 10 mg/mL (NDC 55150-251-10)
On backorder. Recovery: late October 2026. Check wholesalers for inventory
Maker contact: 888-238-7880
- Lidocaine Hydrochloride, Injection, 10 mg/mL (NDC 55150-252-20)
Check wholesalers for inventory
Maker contact: 888-238-7880
- Lidocaine Hydrochloride, Injection, 20 mg/mL (NDC 55150-254-10)
On backorder. Recovery: TBD. Check wholesalers for inventory
Maker contact: 888-238-7880
- Lidocaine Hydrochloride, Injection, 20 mg/mL (NDC 55150-255-20)
Check wholesalers for inventory
Maker contact: 888-238-7880
- Lidocaine Hydrochloride, Injection, 20 mg/mL (NDC 55150-256-50)
On backorder. Recovery: TBD. Check wholesalers for inventory
Maker contact: 888-238-7880
- Lidocaine Hydrochloride And Dextrose, Injection, 5 g/100 mL; .4 g/100 mL (NDC 0264-9594-10)
Maker contact: 800-227-2862
- Lidocaine Hydrochloride And Dextrose, Injection, 5 g/100 mL; .4 g/100 mL (NDC 0264-9594-20)
Maker contact: 800-227-2862
- Lidocaine Hydrochloride And Dextrose, Injection, 5 g/100 mL; .8 g/100 mL (NDC 0264-9598-20)
Maker contact: 800-227-2862
- Lidocaine Hydrochloride Preservative Free In Plastic Container, Injection, 100 mg/5mL (2%,20 mg/1 mL) Syringes (NDC 0409-1323-05)
Maker contact: 844-646-4398
- Lidocaine Hydrochloride, Injection, 100 mg/5 mL (2%; 20 mg/mL) (NDC 0409-2066-05)
Maker contact: 844-646-4398
- Lidocaine Hydrochloride In Plastic Container, Injection, 250 mg/50 mL (0.5%; 5 mg/mL) (NDC 0409-4275-01)
Next Delivery and Estimated Recovery: December 2028; Shortage per Manufacturer: Manufacturing Delay
Maker contact: 844-646-4398
- Lidocaine Hydrochloride In Plastic Container, Injection, 200 mg/20 mL (1%; 10 mg/mL) (NDC 0409-4276-01)
Maker contact: 844-646-4398
- Lidocaine Hydrochloride In Plastic Container, Injection, 500 mg/50 mL (1%; 10 mg/mL) (NDC 0409-4276-02)
Maker contact: 844-646-4398
- Lidocaine Hydrochloride In Plastic Container, Injection, 400 mg/20 mL (2%; 20 mg/mL) (NDC 0409-4277-01)
Maker contact: 844-646-4398
- Lidocaine Hydrochloride In Plastic Container, Injection, 1,000 mg/50 mL (2%; 20 mg/mL) (NDC 0409-4277-02)
Maker contact: 844-646-4398
- Lidocaine Hydrochloride, Injection, 250 mg/50 mL (0.5%; 5 mg/mL) (NDC 0409-4278-01)
Maker contact: 844-646-4398
- Lidocaine Hydrochloride, Injection, 300 mg/30 mL (1%; 10 mg/mL) (NDC 0409-4279-02)
Maker contact: 844-646-4398
- Lidocaine Hydrochloride, Injection, 40 mg/2 mL (2%; 20 mg/mL) (NDC 0409-4282-01)
Maker contact: 844-646-4398
- Lidocaine Hydrochloride, Injection, 200 mg/10 mL (2%; 20 mg/mL) (NDC 0409-4282-02)
Maker contact: 844-646-4398
- Lidocaine Hydrochloride Preservative Free, Injection, 200 mg/5 mL (4%; 40 mg/mL) (NDC 0409-4283-01)
Maker contact: 844-646-4398
- Lidocaine Hydrochloride Preservative Free, Injection, 50 mg/5 mL (1%; 10 mg/mL) (NDC 0409-4713-02)
Maker contact: 844-646-4398
- Lidocaine Hydrochloride Preservative Free, Injection, 20 mg/2 mL (1%; 10 mg/mL) (NDC 0409-4713-32)
Maker contact: 844-646-4398
- Lidocaine Hydrochloride Preservative Free, Injection, 300 mg/20 mL (1.5%; 15 mg/mL) (NDC 0409-4776-01)
Maker contact: 844-646-4398
- Lidocaine Hydrochloride Preservative Free In Plastic Container, Injection, 50 mg/5mL (1%, 10 mg/1 mL) Syringes (NDC 0409-9137-05)
Maker contact: 844-646-4398
- Lidocaine Hydrochloride, Injection, 20 mg/1 mL (NDC 0143-9575-10)
Additional lots are scheduled for manufacturing to meet demand. Product will be made available as it is released.
Maker contact: 800-631-2174
- Lidocaine Hydrochloride, Injection, 10 mg/1 mL (NDC 0143-9577-10)
Additional lots are scheduled for manufacturing to meet demand. Product will be made available as it is released.
Maker contact: 800-631-2174
- Lidocaine Hydrochloride, Preservative Free, Injection, 20 mg/1 mL (NDC 0143-9594-25)
Additional lots are scheduled to be manufactured. Product will be made available as it is released.
Maker contact: 800-631-2174
- Lidocaine Hydrochloride, Preservative Free, Injection, 10 mg/1 mL (NDC 0143-9595-25)
Additional lots are scheduled for manufacturing to meet demand. Product will be made available as it is released.
Maker contact: 800-631-2174
- Lidocaine Hydrochloride, Injection, 20 mg/1 mL (NDC 76329-3390-1)
Available on allocation
Maker contact: 800-423-4136
- Lidocaine Hydrochloride Preservative Free, Injection, 20 mg/1 mL (NDC 63323-208-05)
Next release October 2026. Check wholesalers for inventory.
Maker contact: 888-386-1300
- Xylocaine, Injection, 10 mg/1 mL (NDC 63323-485-57)
Check wholesalers for inventory
Maker contact: 888-386-1300
- Xylocaine, Injection, 20 mg/1 mL (NDC 63323-486-27)
Next release October 2026. Check wholesalers for inventory.
Maker contact: 888-386-1300
- Xylocaine, Injection, 10 mg/1 mL (NDC 63323-492-27)
Next release October 2026. Check wholesalers for inventory.
Maker contact: 888-386-1300
- Xylocaine, Injection, 20 mg/1 mL (NDC 63323-495-07)
Next release September 2026. Check wholesalers for inventory.
Maker contact: 888-386-1300
- Lidocaine Hydrochloride, Injection, 10 mg/1 mL (NDC 73293-0001-2)
Estimated recovery: TBD
Maker contact: intbiz@huons.com
- Lidocaine Hydrochloride, Injection, 10 mg/1 mL (NDC 65282-1605-1)
Estimated recovery: TBD
Maker contact: 978-657-0889 ext. 5231
- Lidocaine Hydrochloride, Injection, 2%, USP (For Cardiac Use Only) 100 mg/5 mL (20 mg/mL) LifeShield® ABBOJECT® Glass Syringe (20 G x 1 1/2) (NDC 0409-4903-34)"
Discontinuation of the manufacture of the drug
Maker contact: 844-646-4398
- Lidocaine Hydrochloride, Injection, 1%, USP (For Cardiac Use Only) 50 mg/5 mL (10 mg/mL) LifeShield™ ABBOJECT® Glass Syringe (20 G x 1 1/2) (NDC 0409-4904-34)"
Discontinuation of the manufacture of the drug
Maker contact: 844-646-4398
FDA recalls of the same active ingredient
Recalls can cause or worsen a shortage. These FDA drug recalls share an active ingredient with Lidocaine Hydrochloride Injection:
- Asclemed USA Inc. recalls Lidocaine HCl Injection USP, 1% (10 mg/mL), 5 mL single dose ampule, Rx Only, Distributed by Enovachem Pharmaceuticals,
- Asclemed USA Inc. recalls Accucaine, Kit contains: Lidocaine HCl Injection USP, 1% (10 mg/mL), 5 mL single dose ampule, Rx Only, Distributed by
- Spectra Medical Devices, Llc recalls Lidocaine HCl Injection USP, 25x5 mL, Single-Dose Ampules, Rx Only, Distributed by: Spectra Medical Devices, LLC,
- Huons Co., Ltd. recalls Lidocaine HCl Injection, USP, 2%, 100 mg/5mL (20 mg/mL), 5 mL Single-Dose Vials, Rx only, Manufactured by: Huons Co.,
- Huons Co., Ltd. recalls Lidocaine HCl injection, USP, 1% 50mg/5mL (10 mg/mL), 5 mL Single Dose Vials, Rx only, Manufactured by: Huons Co, Ltd,
- Fresenius Kabi USA, LLC recalls 5% Dextrose Injection, USP 5 g per 100 mL (50 mg per mL) 100 mL in a 100 mL freeflex bag, Fresenius Kabi USA, LLC
- Fresenius Kabi USA, LLC recalls 5% Dextrose Injection, USP 12.5 g per 250 mL (50 mg per mL) 250 mL in a 250 mL freeflex bag, Fresenius Kabi USA, LLC
- Fresenius Kabi USA, LLC recalls 5% Dextrose Injection, USP 2.5 g per 50 mL (50 mg per mL) 50 mL in a 100 mL freeflex bag, Fresenius Kabi USA, LLC
- Pro Numb Tattoo Numbing Spray LLC recalls Pro Numb Tattoo Numbing Spray, For Sensitive Skin, 4% Lidocaine, [1FL OZ/28.4 ML or 4 oz/120 mL] per bottle,
- Pro Numb Tattoo Numbing Spray LLC recalls Pro Numb Tattoo Numbing Spray, 5% Lidocaine, [1 FL OZ/28.4 ML or 4 oz/120 mL] per bottle, Distributed by: Pro Numb
- Novocol Pharmaceutical of Canada, Inc. recalls Lidocaine HCI 2% and Epinephrine 1:100,000 (Lidocaine HCI and Epinephrine Injection USP), packaged in a carton
- Novocol Pharmaceutical of Canada, Inc. recalls 2% Xylocaine DENTAL with Epinephrine 1:100,000 (Lidocaine HCI and Epinephrine Injection USP), packaged in a carton
Other forms on FDA’s list
- Calcium Chloride; Dextrose; Magnesium Chloride; Sodium Chloride; Sodium Lactate Intraperitoneal Injection, Solution
- Dextrose Monohydrate 10% Injection
- Dextrose Monohydrate 50% Injection
- Dextrose Monohydrate 5% Injection
- Dextrose Monohydrate 70% Injection
- Dextrose Monohydrate, Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride Solution
- Epinephrine Bitartrate, Lidocaine Hydrochloride Injection
- Peritoneal Dialysis Solution
Lidocaine Hydrochloride Injection shortage questions
Is Lidocaine Hydrochloride Injection (Xylocaine) in shortage?
Yes. Lidocaine Hydrochloride Injection is on FDA’s drug shortage list (unavailable), last updated Oct 6, 2026.
Why is there a Lidocaine Hydrochloride Injection shortage?
FDA records the reason as: Demand increase for the drug; Other.
What should I do if I can’t get Lidocaine Hydrochloride Injection?
Don’t stop or ration it on your own. Ask your pharmacist whether another strength, package size or maker is in stock, and ask your prescriber about an alternative if none is.
Source: FDA Drug Shortages Database via openFDA. FDA notes that openFDA data is unvalidated and should not be used to make decisions about medical care; ask your pharmacist or prescriber before changing any medication. FDA Drug Shortages Database.