Is Bupivacaine Hydrochloride Injection (Marcaine) in shortage?
Yes. Bupivacaine Hydrochloride Injection is on FDA’s drug shortage list (unavailable), last updated Oct 6, 2026.
Why it’s in shortage
- Delay in shipping of the drug
- Demand increase for the drug
- Discontinuation of the manufacture of the drug
- Other
Every listed package
FDA tracks shortages per package. What each maker reports, most recently updated first:
- Sensorcaine, Injection, 2.5 mg/1 mL (NDC 63323-464-17)
Check wholesalers for inventory
Maker contact: 888-386-1300
- Sensorcaine, Injection, 2.5 mg/1 mL (NDC 63323-464-31)
Estimated recovery: TBD
Maker contact: 888-386-1300
- Sensorcaine, Injection, 2.5 mg/1 mL (NDC 63323-464-37)
Check wholesalers for inventory
Maker contact: 888-386-1300
- Sensorcaine, Injection, 2.5 mg/1 mL (NDC 63323-465-57)
Check wholesalers for inventory
Maker contact: 888-386-1300
- Sensorcaine, Injection, 5 mg/1 mL (NDC 63323-466-17)
Check wholesalers for inventory
Maker contact: 888-386-1300
- Sensorcaine, Injection, 5 mg/1 mL (NDC 63323-466-31)
Estimated recovery: TBD
Maker contact: 888-386-1300
- Sensorcaine, Injection, 5 mg/1 mL (NDC 63323-466-37)
Check wholesalers for inventory
Maker contact: 888-386-1300
- Sensorcaine, Injection, 5 mg/1 mL (NDC 63323-467-57)
Check wholesalers for inventory
Maker contact: 888-386-1300
- Sensorcaine, Injection, 7.5 mg/1 mL (NDC 63323-472-17)
Check wholesalers for inventory
Maker contact: 888-386-1300
- Sensorcaine, Injection, 7.5 mg/1 mL (NDC 63323-472-37)
Check wholesalers for inventory
Maker contact: 888-386-1300
- Bupivacaine Hydrochloride, Injection, 2.5 mg/1 mL (NDC 55150-167-10)
Check wholesalers for inventory
Maker contact: 888-238-7880
- Bupivacaine Hydrochloride, Injection, 2.5 mg/1 mL (NDC 55150-168-30)
Check wholesalers for inventory
Maker contact: 888-238-7880
- Bupivacaine Hydrochloride, Injection, 5 mg/1 mL (NDC 55150-169-10)
Check wholesalers for inventory
Maker contact: 888-238-7880
- Bupivacaine Hydrochloride, Injection, 5 mg/1 mL (NDC 55150-170-30)
Check wholesalers for inventory
Maker contact: 888-238-7880
- Bupivacaine Hydrochloride, Injection, 7.5 mg/1 mL (NDC 55150-171-10)
Check wholesalers for inventory
Maker contact: 888-238-7880
- Bupivacaine Hydrochloride, Injection, 7.5 mg/1 mL (NDC 55150-172-30)
Check wholesalers for inventory
Maker contact: 888-238-7880
- Bupivacaine Hydrochloride, Injection, 2.5 mg/1 mL (NDC 55150-249-50)
Check wholesalers for inventory
Maker contact: 888-238-7880
- Bupivacaine Hydrochloride, Injection, 5 mg/1 mL (NDC 55150-250-50)
Check wholesalers for inventory
Maker contact: 888-238-7880
- Marcaine, Injection, 250 mg/50 mL (NDC 0409-0525-25)
Historical NDC: 0409-1610-50
Maker contact: 844-646-4398
- Bupivacaine Hydrochloride, Injection, 25 mg/10 mL (2.5 mg/mL) (NDC 0409-1159-01)
Maker contact: 844-646-4398
- Bupivacaine Hydrochloride, Injection, 75 mg/30 mL (2.5 mg/mL) (NDC 0409-1159-02)
Maker contact: 844-646-4398
- Bupivacaine Hydrochloride, Injection, 125 mg/50 mL (2.5 mg/mL) (NDC 0409-1160-01)
Maker contact: 844-646-4398
- Bupivacaine Hydrochloride, Injection, 50 mg/10 mL (5 mg/mL) (NDC 0409-1162-01)
Maker contact: 844-646-4398
- Bupivacaine Hydrochloride, Injection, 150 mg/30 mL (5 mg/mL) (NDC 0409-1162-02)
Maker contact: 844-646-4398
- Bupivacaine Hydrochloride, Injection, 250 mg/50 mL (5 mg/mL) (NDC 0409-1163-01)
Maker contact: 844-646-4398
- Marcaine, Injection, Marcaine 75 mg/10 mL (7.5 mg/mL) (NDC 0409-1165-01)
Maker contact: 844-646-4398
- Bupivacaine Hydrochloride, Injection, 225 mg/30 mL (7.5 mg/mL) (NDC 0409-1165-02)
Maker contact: 844-646-4398
- Marcaine, Injection, 150 mg/30 mL (5 mg/mL) (NDC 0409-1530-01)
Maker contact: 844-646-4398
- Marcaine, Injection, 0.75% 15 mg/2 mL (7.5 mg/mL) in Dextrose 8.25% (NDC 0409-1761-10)
Next Delivery: November 2026; Estimated Recovery: December 2026; Shortage per Manufacturer: Manufacturing Delay
Maker contact: 844-646-4398
- Marcaine, Injection, 0.75% 15 mg/2 mL (NDC 0409-1761-62)
Maker contact: 844-646-4398
- Marcaine, Injection, Marcaine 225 mg/30 mL (7.5 mg/mL) (NDC 0409-2253-01)
Historical NDC: 0409-1582-29
Maker contact: 844-646-4398
- Marcaine, Injection, 225 mg/30 mL (NDC 0409-2253-25)
Historical NDC: 0409-1582-29
Maker contact: 844-646-4398
- Marcaine, Injection, 25 mg/10 mL (2.5 mg/mL) (NDC 0409-2510-01)
Maker contact: 844-646-4398
- Bupivacaine Hydrochloride, Injection, Bupivacaine Spinal 15 mg/2 mL (7.5 mg/mL in 8.25% dextrose) (NDC 0409-3613-01)
Limited Supply Available. Next Delivery: May 2027; Estimated Recovery: June 2027
Maker contact: 844-646-4398
- Marcaine, Injection, 50 mg/10 mL (5 mg/mL) (NDC 0409-5010-01)
Maker contact: 844-646-4398
- Marcaine, Injection, 75 mg/30 mL (2.5 mg/mL) (NDC 0409-7535-01)
Maker contact: 844-646-4398
- Bupivacaine Hydrochloride PRESERVATIVE FREE, Injection, 2.5 mg/1 mL 5mg / 1mL (NDC 72266-263-10)
Distributed by Fosun Pharma USA Inc.
Maker contact: 888-217-8103
- Bupivacaine Hydrochloride, Injection, 2.5 mg/1 mL (NDC 70069-752-01)
Maker contact: 732-554-1037
- Bupivacaine Hydrochloride, Injection, 2.5 mg/1 mL (NDC 70069-752-10)
Maker contact: 732-554-1037
- Bupivacaine Hydrochloride, Injection, 2.5 mg/1 mL (NDC 70069-752-25)
Maker contact: 732-554-1037
- Bupivacaine Hydrochloride, Injection, 5 mg/1 mL (NDC 70069-753-01)
Maker contact: 732-554-1037
- Bupivacaine Hydrochloride, Injection, 5 mg/1 mL (NDC 70069-753-10)
Maker contact: 732-554-1037
- Bupivacaine Hydrochloride, Injection, 5 mg/1 mL (NDC 70069-753-25)
Maker contact: 732-554-1037
- Bupivacaine Hydrochloride, Injection, 7.5 mg/1 mL (NDC 73293-0002-2)
Estimated recovery: TBD
Maker contact: +82-2-854-4700 or via email intbiz@huons.com
- Bupivacaine Hydrochloride, Injection, 2.5 mg/1 mL (NDC 31722-275-32)
Maker contact: 732-529-0430, customerservice@camberpharma.com
- Bupivacaine Hydrochloride, Injection, 2.5 mg/1 mL (NDC 31722-275-34)
Maker contact: 732-529-0430, customerservice@camberpharma.com
- Bupivacaine Hydrochloride, Injection, 5 mg/1 mL (NDC 31722-276-32)
Maker contact: 732-529-0430, customerservice@camberpharma.com
- Bupivacaine Hydrochloride, Injection, 5 mg/1 mL (NDC 31722-276-34)
Maker contact: 732-529-0430, customerservice@camberpharma.com
- Bupivacaine Hydrochloride, Injection, 7.5 mg/1 mL (NDC 31722-277-32)
Maker contact: 732-529-0430, customerservice@camberpharma.com
- Bupivacaine Hydrochloride, Injection, 7.5 mg/1 mL (NDC 31722-277-34)
Maker contact: 732-529-0430, customerservice@camberpharma.com
- Bupivacaine Hydrochloride, Injection, 2.5 mg/1 mL (NDC 71288-723-52)
Meitheal Pharmaceuticals is distributor/labeler More from the maker
Maker contact: 844-824-8426
- Bupivacaine Hydrochloride, Injection, 5 mg/1 mL (NDC 71288-725-32)
Meitheal Pharmaceuticals is distributor/labeler More from the maker
Maker contact: 844-824-8426
- Bupivacaine Hydrochloride, Injection, 5 mg/1 mL (NDC 71288-726-52)
Meitheal Pharmaceuticals is distributor/labeler More from the maker
Maker contact: 844-824-8426
- Bupivacaine Hydrochloride, Injection, 7.5 mg/1 mL (NDC 71288-728-32)
Meitheal Pharmaceuticals is distributor/labeler More from the maker
Maker contact: 844-824-8426
- Bupivacaine Hydrochloride, Injection, 2.5 mg/1 mL (NDC 71288-722-32)
Discontinuation of the manufacture of the drug
Maker contact: 844-824-8426
FDA recalls of Bupivacaine Hydrochloride
Recalls can cause or worsen a shortage. These FDA drug recalls share an active ingredient with Bupivacaine Hydrochloride Injection:
- Huons Co., Ltd. recalls Bupivacaine Hydrochloride 0.75% in 8.25% Dextrose Injection, USP (15 mg/2 mL) (7.5 mg/mL) ampules, Rx only,
- Fresenius Kabi USA, LLC recalls Sensorcaine (Bupivacaine HCl and Epinephrine Injection, USP) with Epinephrine 1:200,000 (as bitartrate), 0.25%, 125 mg
- Fresenius Kabi USA, LLC recalls Sensorcaine-MPF (Bupivacaine HCl and Epinephrine Injection, USP) with Epinephrine 1:200,000 (as bitartrate), 0.25%, 25
- Fresenius Kabi USA, LLC recalls Sensorcaine (Bupivacaine HCl and Epinephrine Injection, USP) with Epinephrine 1:200,000 (as bitartrate), 0.5%, 250 mg
- Mckesson Medical-Surgical Inc. Corporate Office recalls Bupivacaine HCl Injection, single dose vial, Preservative Free 0.5%, 10mL (25/ct), Rx only, Manufacturer: Auromedics
- Mckesson Medical-Surgical Inc. Corporate Office recalls Bupivacaine Hydrochloride, USP 0.5% (5mg/mL), 25 vials x 50 mL per box, Rx only, MFG: Pfizer, NDC 0409-1163-01
- PFIZER, INC recalls 0.5% Bupivacaine Hydrochloride Injection, USP, 150 mg/30 mL (5 mg/mL), 30 mL Single-dose Teartop Vials (NDC
- Fresenius Kabi USA, LLC recalls Sensorcaine-MPF (Bupivacaine HCl and Epinephrine Injection, USP), 0.5%, 150 mg per 30 mL (5 mg per mL), 30 mL Single
- Hospira Inc., A Pfizer Company recalls Marcaine 0.5% (bupivacaine HCl) injection, USP, 250 mg/50 mL (5 mg/mL), 50 mL Multiple-Dose Vial, Rx only, Hospira,
- Hospira Inc., A Pfizer Company recalls Marcaine 0.25% (bupivacaine HCl) injection, USP, 125 mg/50 mL (2.5 mg/mL), 50 mL Multiple-Dose Vial, Rx only, Hospira,
- Hospira Inc., A Pfizer Company recalls Bupivacaine Hydrochloride Inj., USP (2.5 mg/mL) 0.25%, packaged in 30 mL Single-dose Preservative-Free vials, Rx Only,
- Fresenius Kabi USA, LLC recalls Sensorcaine- MPF (Bupivacaine HCI Injection, USP), 0.75% in a 30 mL Single Dose Vial, Rx only, Fresenius Kabi USA LLC,
Other forms on FDA’s list
Bupivacaine Hydrochloride Injection shortage questions
Is Bupivacaine Hydrochloride Injection (Marcaine) in shortage?
Yes. Bupivacaine Hydrochloride Injection is on FDA’s drug shortage list (unavailable), last updated Oct 6, 2026.
Why is there a Bupivacaine Hydrochloride Injection shortage?
FDA records the reason as: Delay in shipping of the drug; Demand increase for the drug; Discontinuation of the manufacture of the drug; Other.
What should I do if I can’t get Bupivacaine Hydrochloride Injection?
Don’t stop or ration it on your own. Ask your pharmacist whether another strength, package size or maker is in stock, and ask your prescriber about an alternative if none is.
Source: FDA Drug Shortages Database via openFDA. FDA notes that openFDA data is unvalidated and should not be used to make decisions about medical care; ask your pharmacist or prescriber before changing any medication. FDA Drug Shortages Database.