Orexigen Therapeutics, Inc. recalls Contrave (naltrexone HCl and bupropion HCl) Extended-Release Tablets, 8 mg/90 mg, 120-count bottle, Rx only,
Orexigen recalls Contrave 8mg/90mg tablets due to customer reports of bottle punctures. Affected lots expire Nov 2020. Stop using if you have these bottles.
Use caution until it’s fixed
Defective Container: Customer complaints of punctures in the bottle.
Contact the company & request your remedy
What happened, in plain English
Orexigen is recalling Contrave (naltrexone HCl and bupropion HCl) tablets because customers reported punctures in the bottles. This could lead to accidental medication exposure or contamination if the bottle is damaged. Read more at govinfonow.com/recall/39745-orexigen-contrave-tablets-recall-puncture-risk-in-bottles.
Source Summary by GovInfoNow · govinfonow.com/recall/39745-orexigen-contrave-tablets-recall-puncture-risk-in-bottles · Updated October 6, 2026 · FDA enforcement record: FDA #D-1099-2018
Cite this page
“Orexigen Contrave Tablets Recall: Puncture Risk in Bottles.” GovInfoNow, updated October 6, 2026. https://govinfonow.com/recall/39745-orexigen-contrave-tablets-recall-puncture-risk-in-bottles. Based on FDA recall #D-1099-2018 (https://api.fda.gov/drug/enforcement.json?search=recall_number:%22D-1099-2018%22&limit=1).
Why it’s dangerous
The bottles have been reported to puncture, which could allow medication to leak or contaminate the area. This might lead to accidental exposure or improper dosing if the bottle is damaged.
Who’s affected
People with prescriptions for Contrave tablets who received bottles with lot numbers ZCXM through ZCXV (expiring November 2020) are affected. Those who have the bottles are most at risk.
How to tell if you have this one
Check for bottles labeled with lot numbers ZCXM, ZCXN, ZCXP, ZCXS, ZCXT, or ZCXV that expire in November 2020. These are the affected lots of Contrave tablets.
- Brand
Orexigen- Category
Drug
What to do — step by step
Check Bottle Lot Number
Look for the lot number on the bottle label, which should be one of ZCXM, ZCXN, ZCXP, ZCXS, ZCXT, or ZCXV.
Stop Using if Punctured
If the bottle shows signs of punctures, stop using the tablets immediately and contact your healthcare provider.
Questions people ask
Why is this recall happening?
Customers have reported punctures in the bottles, which could lead to medication leakage or contamination.
Which lots are affected?
Lots ZCXM through ZCXV that expire in November 2020.
Do I need to return the tablets?
The recall does not specify a return process, but you should stop using the tablets if the bottle is punctured.
Contact Orexigen
We’ve drafted a message you can send Orexigen to request your refund or repair — edit it as you like.
Subject: Recall D-1099-2018 — Orexigen Orexigen Hello, I own a Orexigen that is covered by recall D-1099-2018 from Orexigen. I’m writing to arrange the remedy described in the recall (a refund, repair, or replacement as applicable). Could you please tell me the next steps to resolve this? Thank you.
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Where this comes from
The facts (hazard, remedy, dates, manufacturer) are pulled from the official FDA recall record. The plain-language summary and step-by-step checklist are written by GovInfoNow to make the official notice easier to act on — they don’t replace it.
- Official source: FDA Recall #D-1099-2018 (August 9, 2018) — FDA publishes no per-recall page; this is the official machine-readable enforcement record. Search FDA recalls for D-1099-2018 to see it in context.
- Plain-language summary written by qwen3:4b on October 6, 2026, from the official record above. Not reviewed by a person — if it conflicts with the FDA notice, the notice is correct. Report an error on this page.
- GovInfoNow is an independent service and is not a government agency. We republish official FDA recall data; we don’t issue, amend or administer recalls.