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FDA drug shortage status

Is Promethazine Hydrochloride Injection (Phenergan) in shortage?

Yes. Promethazine Hydrochloride Injection is on FDA’s drug shortage list (unavailable), last updated Sep 22, 2026.

In shortageFDA status
10packages listed
6unavailable

Why it’s in shortage

  • Demand increase for the drug
  • Other

Every listed package

FDA tracks shortages per package. What each maker reports, most recently updated first:

  • Promethazine Hydrochloride, Injection, 25 mg/1 mL (NDC 39822-5525-3)
    XGen Pharmaceuticals DJB, Inc.In shortageAvailableUpdated Sep 22, 2026

    Maker contact: 866-390-4411

  • Promethazine Hydrochloride, Injection, 50 mg/1 mL (NDC 39822-5550-6)
    XGen Pharmaceuticals DJB, Inc.In shortageUnavailableUpdated Sep 22, 2026

    Estimated recovery: TBD

    Maker contact: 866-390-4411

  • Promethazine Hydrochloride, Injection, 25 mg/1 mL (NDC 0641-0928-25)
    Hikma Pharmaceuticals USA, Inc.In shortageUnavailableUpdated Sep 18, 2026

    Additional lots will be available in the October 2026 timeframe. Product will be made available as it is released.

    Maker contact: 800-631-2174

  • Promethazine Hydrochloride, Injection, 50 mg/1 mL (NDC 0641-0929-25)
    Hikma Pharmaceuticals USA, Inc.In shortageLimited AvailabilityUpdated Sep 18, 2026

    Estimated recovery: TBD

    Maker contact: 800-631-2174

  • Promethazine Hydrochloride, Injection, 25 mg/1 mL (NDC 0641-1495-35)
    Hikma Pharmaceuticals USA, Inc.In shortageAvailableUpdated Sep 18, 2026

    Limited availability

    Maker contact: 800-631-2174

  • Promethazine Hydrochloride, Injection, 50 mg/1 mL (NDC 0641-1496-35)
    Hikma Pharmaceuticals USA, Inc.In shortageAvailableUpdated Sep 18, 2026

    Additional lots are scheduled to be manufactured. Product will be made available as it is released.

    Maker contact: 800-631-2174

  • Phenergan, Injection, 25 mg/1 mL (NDC 0641-6082-25)
    Hikma Pharmaceuticals USA, Inc.In shortageUnavailableUpdated Sep 18, 2026

    Additional lots are scheduled to be manufactured. Product will be made available as it is released.

    Maker contact: 800-631-2174

  • Phenergan, Injection, 50 mg/1 mL (NDC 0641-6083-25)
    Hikma Pharmaceuticals USA, Inc.In shortageUnavailableUpdated Sep 18, 2026

    Additional lots are scheduled to be manufactured. Product will be made available as it is released.

    Maker contact: 800-631-2174

  • Phenergan, Injection, 25 mg/1 mL (NDC 0641-6084-25)
    Hikma Pharmaceuticals USA, Inc.In shortageUnavailableUpdated Sep 18, 2026

    Estimated recovery: TBD

    Maker contact: 800-631-2174

  • Phenergan, Injection, 50 mg/1 mL (NDC 0641-6085-25)
    Hikma Pharmaceuticals USA, Inc.In shortageUnavailableUpdated Sep 18, 2026

    Estimated recovery: TBD

    Maker contact: 800-631-2174

FDA recalls of Promethazine Hydrochloride

Recalls can cause or worsen a shortage. These FDA drug recalls share an active ingredient with Promethazine Hydrochloride Injection:

Promethazine Hydrochloride Injection shortage questions

Is Promethazine Hydrochloride Injection (Phenergan) in shortage?

Yes. Promethazine Hydrochloride Injection is on FDA’s drug shortage list (unavailable), last updated Sep 22, 2026.

Why is there a Promethazine Hydrochloride Injection shortage?

FDA records the reason as: Demand increase for the drug; Other.

What should I do if I can’t get Promethazine Hydrochloride Injection?

Don’t stop or ration it on your own. Ask your pharmacist whether another strength, package size or maker is in stock, and ask your prescriber about an alternative if none is.

Source: FDA Drug Shortages Database via openFDA. FDA notes that openFDA data is unvalidated and should not be used to make decisions about medical care; ask your pharmacist or prescriber before changing any medication. FDA Drug Shortages Database.