Is Alteplase Injection (Activase) in shortage?
Alteplase Injection is listed by FDA as being discontinued by at least one maker (updated May 21, 2026).
Every listed package
FDA tracks shortages per package. What each maker reports, most recently updated first:
- Activase, Injection, 1 KIT in 1 CARTON (50242-085-27) * 100 mL in 1 VIAL, SINGLE-USE * 100 mL in 1 VIAL, SINGLE USE (NDC 50242-085-27)
Discontinuation of the 100mg vial configuration
Maker contact: 800-551-2231
Alteplase Injection shortage questions
Is Alteplase Injection (Activase) in shortage?
Alteplase Injection is listed by FDA as being discontinued by at least one maker (updated May 21, 2026).
What should I do if I can’t get Alteplase Injection?
Don’t stop or ration it on your own. Ask your pharmacist whether another strength, package size or maker is in stock, and ask your prescriber about an alternative if none is.
Source: FDA Drug Shortages Database via openFDA. FDA notes that openFDA data is unvalidated and should not be used to make decisions about medical care; ask your pharmacist or prescriber before changing any medication. FDA Drug Shortages Database.